About Texas State Library Maps Round Rock

Texas State Links

adjust type size

make font smaller

make font larger

reset font size

Texas State > College of Science and Engineering > Chemistry & Biochemistry > Contacts > Faculty > Dr. Kevin Lewis - Associate Professor > Selected Publications

Selected Publications

Gary W. Beall, Drew S. Sowersby, Rachel D. Roberts, Michael H. Robson and L. Kevin Lewis*. 2008. Analysis of oligonucleotide DNA binding and sedimentation properties of montmorillonite clay using ultraviolet light spectroscopy. Submitted to journal Biomacromolecules.
Brian M. Wasko, Cory L. Holland, Michael A. Resnick and L. Kevin Lewis*. 2008. Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae. Submitted to journal DNA Repair.
Brian M. Wasko, Jared R. Cassiano, Michael A. Resnick, and L. Kevin Lewis*. 2007. Stimulation of DNA repair by telomerase RNA reveals multiple sources of damage sensitivity in mrx nuclease mutants. Submitted to journal Genetics.
L. Kevin Lewis*, Kirill Lobachev, James W. Westmoreland, Kelly M. Williamson and Michael A. Resnick. 2005. Use of a restriction endonuclease cytotoxicity assay to identify inducible GAL1 promoter variants with reduced basal activity. Gene. 363:183-192.
L. Kevin Lewis*, Karthikeyan Gopalakrishnan, Jared Cassiano, and Michael A. Resnick. 2005. Reduction of nucleosome assembly during new DNA synthesis impairs both major pathways of double-strand break repair. Nucleic Acids Res. 33:4928-4939.
Chen, L., Kelly M. Trujillo, Stephen Van Komen, Dong Roh, Lumir Krejci, L. Kevin Lewis, Michael A. Resnick, Patrick Sung, and Alan E. Tomkinson. 2005. Effect of amino acid substitutions in the Rad50 ATP binding domain on DNA double strand break repair. J Biol Chem. 280:2620-2627.
L. Kevin Lewis*, Francesca Storici, Shanna Calero and Michael A. Resnick. 2004. Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells. Genetics 166:1701-1713.
L. Kevin Lewis*, James Westmoreland, and Michael A. Resnick. 2002. Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase). Genetics 160:49-62.
Karthikeyan Gopalakrishnan, L. Kevin Lewis, and Michael A. Resnick. 2002. The mitochondrial protein frataxin prevents nuclear DNA instability. Human Molecular Genetics 11:1351-1362.
Craig B. Bennett, L. Kevin Lewis, Gopalakrishnan Karthikeyan, Kirill Lobachev, Yohan Jin, and Michael A. Resnick. 2001. Genes required for ionizing radiation resistance in yeast. Nature Genetics 29:426-434.
Francesca Storici, L. Kevin Lewis, and Michael A. Resnick. 2001. In vivo site-directed mutagenesis using oligonucleotides. Nature Biotechnol. 19:773-776.
L. Kevin Lewis and Michael A. Resnick. 2000. Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae. Mutat Res 451:71-89.
L. Kevin Lewis, James Westmoreland, and Michael A. Resnick. 1999. Repair of endonuclease-induced double-strand breaks in Saccharomyces cerevisiae: essential role for genes associated with nonhomologous end-joining. Genetics 152:1513-1529.
L. Kevin Lewis, Jakob M. Kirchner, and Michael A. Resnick. 1998. Requirement for end-joining and checkpoint functions, but not RAD52-mediated recombination, after EcoRI endonuclease cleavage of Saccharomyces cerevisiae DNA. Mol Cell Biol 18:1891-1902.

Graduate Theses Completed in the Lewis Lab:

2008: Cory Holland – “Role of telomerase in regulation of chromosome stability in cells lacking the Ku70/Ku80 heterodimer”
2008: Rachel Roberts – “Development of new assays to identify Saccharomyces cerevisiae genes required for efficient repair of a single site-specific DNA double-strand break”
2008: Jennifer Summers – “Application of a novel endonuclease sensitivity assay to identify new genes that affect DNA repair and chromosome statbility”
2007: Sandra Becerra – “Mechanism of establishment and bypass of in vitro cell aging”
2006: Alison Russell – “Role of reactive oxygen species and altered biochemical pathways in cellular aging”
2006: Brian Wasko -“Interactions between double-strand break repair proteins and the telomerase DNA replication complex”
2005: Hiranthi Thambugala – “Use of a new regulatable telomerase expression system to monitor in vitro cell aging and the effects of DNA damage on replicative senescence”
2004: Jared Cassiano -“DNA damage resistance determined by interplay between telomerase and DNA repair complexes”
2003: Shanna Calero “Repair of DNA double-strand breaks in chromosomes: impact of telomerase”
2003: Natashya Waring – “Isolation and characterization of DNA polymerase epsilon mutants affecting DNA replication, repair and cell cycle checkpoints in Saccharomyces cerevisiae”