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Selected Publications

Irvin, J. D., "Purification and Partial Characterization of the Antiviral Protein from Phytolacca Americana Which Inhibits Protein Synthesis," Archives Biochem. Biophys. 169, 522-528 (1975).
Gessner, S.L. and Irvin, J. D., "Inhibition of Elongation Factor 2-Dependent Translocation by the Pokeweed Antiviral Protein and Ricin," J. Biol. Chem., 225, 2351-2353 (1980).
Irvin, J. D., "Pokeweed Antiviral Protein," Pharmac. Ther., 21, 371-387 (1983).
Taylor, B. E. and Irvin, J. D., "Depurination Of Plant Ribosomes by Pokeweed Antiviral Protein" FEBS Letters 273, 144-146 (1990).
Meyers, D. E., Irvin, J. D., Smith, R. S., Kuebelbeck, V. M., Tuel-Ahlgren, L., and Uckun, F. M., "Large Scale Production of a Pokeweed Antiviral Protein (PAP) Containing Immunotoxin, B43-PAP, Directed Against the CD19 Human B-Lineage Differentiation Antigen" J. Immunol. Methods 136, 221-38 (1991).
Irvin, J. D. and Uckun, F. M. Pokeweed Antiviral Protein: Ribosome Inactivation and Therapeutic Applications. Pharm. Ther. 55, 279-302 (1992).
Monzingo, A. F., Collins, E. J., Ernst, S. R., Irvin, J. D. and Robertus, J. D., The 2.5 Å Structure of Pokeweed Antiviral Protein, J. Mol. Biol., 233, 705-715 (1993).
Bonness, M. S., Ready, M. P., Irvin, J. D. and Mabry, T. J., Pokeweed Antiviral Protein Inactivates Pokeweed Ribosomes: Implications for Antiviral Mechanism. The Plant Journal, 5, 173-183 (1994).
Irvin, J. D. Antiviral Proteins from Phytolacca in Antiviral Proteins in Higher Plants, M. Chessin, D. DeBrode and A. Zipf, eds. CRC Press, Boca Raton, FL, 65-94, (1995).
Waurzyniak, B., Schneider, E. A., Tumer, N, Yanishevski, Y., Gunther, R., Chelstrom, L. M., Rajamohan, F., Venkatachalam, T. K., Irvin, J. D. and Uckun, F. M. Pokeweed antiviral protein i soforms PAP-I, PAP-II and PAP-III depurinate RNA from human immunodeficiency virus (HIV)-1. Biochem. Biophys. Res. Comm., 260, 453-458 (1999).