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Selected Publications


Howard, R.; Plyler, J. R.; Williams, S.; Araki, N.; David, W. M. “Optimization of SPR-based assay for monitoring SV40 large T-antigen helicase activity,” FASEB J., 2009, 23, 860.1
Jasheway, K.; Plyler, J.; Brennan, J. S.; Karr, J.; Kerwin, S. M.; David, W. M.* “Real-time Investigation of Simian Virus 40 Large T-antigen Helicase Activity by Surface Plasmon Resonance,” Cell Biochem. Biophys., 2009, 53, 43-52.
Tuesuwan, B.; Kern, J. T.; Thomas, P. W.; Rodriguez, M.; Li, J.; David, W. M.; Kerwin, S. M.* "Simian Virus 40 Large T-Antigen G-Quadruplex DNA Helicase Inhibition by G-Quadruplex DNA-Interactive Agents," Biochemistry, 2008, 47, 1896-1909.
David, W.M., David L.M., and R.B. Walter, “DNA Repair in Hybrid Fish of the Genus Xiphophorus,” Comp. Biochem. Physiol., 2004, 138(3), 300-310.
Oehlers, L.P., Heater, S.H., J., Rains, J.D., Wells, M.C., David, W.M., and R.B. Walter, “Gene structure, Purification, and Characterization of DNA polymerase ß from Xiphophorus maculatus,” Comp, Biochem. Physiol., 2004, 138(3), 311-324.
Hennrich, G., David, W.M., Bomble, Y.J., Anslyn, E.V., Brodbelt, J.S., and J.F. Stanton, “Self-assembling Dimeric and Trimeric Aggregates Based on Solvophobic and Charge-pairing Interactions,” Supramolecular Chem., 2004, 16, 521-528.
David, W. M.; Brodbelt, J. S. “Threshold Dissociation Energies of Protonated Amine/Polyether Complexes in a Quadrupole Ion Trap.” J. Am. Soc. Mass Spectrom., 2003, 14, 383-392.
Nadipuram, A. K.; David, W. M.; Kumar, D.; Kerwin, S. M. “Synthesis and Thermolysis of Heterocyclic 3-Aza-3-ene-1,5-diynes.” Organic Lett., 2002, 4, 4543-4546.
David, W. M.; Brodbelt, J.; Kerwin, S. M.; Thomas, P. W. “Investigation of Quadruplex Oligonucleotide-Drug Interactions by Electrospray Ionization-Mass Spectrometry.” Anal. Chem., 2002, 74, 2029-2033.
Tuntiwechapikul, W.; David, W. M.; Kumar, D.; Salazar, M.; Kerwin, S. M. “DNA Modification by 4-Aza-3-ene-1,6-diynes: DNA Cleavage, pH-Dependent Cytosine-Specific Interactions, and Cancer Cell Cytotoxicity.” Biochemistry, 2002, 41, 5283-5290.
Paquette, L. A.; Ra, C. S.; Galluci, J. C.; Kang, H.-J.; Ohmori, N.; Arrington, M.; David, W.; Brodbelt, J. “Constraining of Small-Ring Cyclic Ether Triads by Stereodefined Spiroannulation to an Inositol Orthoformate Platform. Solution and Gas-Phase Alkali Metal Binding Affinities for 3- to 5-Membered Ring Structural Combinations.” J. Org. Chem., 2001, 66, 8629-8639.
Kumar, D.; David, W. M.; Kerwin, S. M. ”N-Propargyl-2-alkylbenzothiazolium Aza-enediynes: Role of the 2-alkylbenzothiazolium Functionality in DNA Cleavage.” Bioorg. Med. Chem. Lett., 2001, 11, 2971-2974.
Kerwin, S. M.; David, W. M.; Kumar, D. DNA Cleavage Anti-tumor Agents, US (2001) Patent 6,297,284 B1
Kerwin, S. M.; David, W. M, Kumar, D. Aza-enediyne, aza-enyne allene, and aza-diallene DNA-cleaving Antitumor Agents, US (2001) Cont-in-part Patent 6,297,284 B1.
David, W. M.; Kumar, D.; Kerwin, S. M. “Synthesis of a Heterocyclic Aza-enediyne and its DNA-cleavage Properties.” Bioorg. Med. Chem. Lett., 2000, 10, 2509-2512.
David, W. M.; Kerwin, S. M. “Synthesis and Thermal Rearrangement of C, N,-Dialkynyl Imines: A Potential Aza-Bergman Route to 2,5-Didehydropyridine.” J. Am. Chem. Soc., 1997, 119, 1464-1465.